IgM rheumatoid factor plaque-forming cells in juvenile rheumatoid arthritis
نویسندگان
چکیده
منابع مشابه
Hidden 19S IgM rheumatoid factor in adults with juvenile rheumatoid arthritis onset.
Forty-eight adult patients with juvenile rheumatoid arthritis (JRA) (onset before age 16 years) were evaluated at the age of 17 years or more for the presence of hidden 19S IgM rheumatoid factors (RF), i.e., 19S IgM RF that can be detected by the complement-dependent haemolytic assay in the IgM-containing fraction after separation of the serum by acid gel filtration. The average age of the pati...
متن کاملIncrease in CD5+ B cells in juvenile rheumatoid arthritis. Relationship to IgM rheumatoid factor expression and disease activity.
OBJECTIVE To investigate the association between CD5+ B cell expression and IgM rheumatoid factor (IgM-RF) in juvenile rheumatoid arthritis (JRA). METHODS CD5+ B cell levels analyzed by flow cytometry and IgM-RF expression determined by enzyme-linked immunosorbent assay were compared in children with JRA, children with other collagen vascular diseases, and healthy controls. RESULTS Children...
متن کاملImmunoglobulin E-rheumatoid factor in juvenile rheumatoid arthritis.
OBJECTIVES To determine the presence of immunoglobulin E-rheumatoid factor in patients with juvenile rheumatoid arthritis and to correlate it with clinical and laboratory parameters. METHODS A multicenter prospective study was carried out from January 1993 to January 1999 with the enrollment of 3 centers of pediatric rheumatology. Ninety-one children with juvenile rheumatoid arthritis diagnos...
متن کاملAntiperinuclear factor in juvenile rheumatoid arthritis.
The serological diagnosis of juvenile rheumatoid arthritis (JRA) is difficult, with only 7-10% of patients 19S IgM rheumatoid factor positive. About 60-70% of patients are positive for hidden 19S IgM rheumatoid factor, but this test requires serum separation and is not available in most laboratories. Antiperinuclear factor has been described in both seropositive and seronegative adult patients ...
متن کاملIgG, IgA, IgM, and IgD antiglobulins in juvenile rheumatoid arthritis.
Usual techniques for the detection of antigammaglobulin factors (DAT, SCAT, HEAT, Latex FII) are based upon agglutination reactions and are therefore useful when IgM antibodies are involved. It is well known that antiglobulins also belong to IgG and IgA classes. In our experience, 50 per cent. of patients with JRA are persistently seronegative when sera are tested only with conventional aggluti...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1987
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780300313